info
慶應医学会例会
下記により例会を開催いたしますので、多数ご来聴ください。
2024年11月5日（火） 18:00 開催
演者の都合により来日できなくなったため、中止となりました
場 所
臨床研究棟ラウンジ
演 題
Intriguing Clinical Cases: Lessons from the University of Texas Medical Branch
Wilkerson G Michael M.D., M.S., FAAD
University of Texas Medical Branch
University of Texas Medical Branch
The University of Texas Medical Branch was founded in Galveston, Texas in 1891. It is the oldest Medical School in Texas and is the original Medical School for the University of Texas System based in Austin, Texas. The Department of Dermatology was started in 1920 and is celebrating its 105th anniversary this year. I understand they the Keio Department of Dermatology was started at the same time. This talk will utilize outstanding clinical cases both from our hospital consultations and outpatient clinics. The Houston area is the 3rd largest metropolitan area in the USA. It is a multinational diverse population with representation from almost every country in the world. We will examine several cases of unique infectious agents seen in our port of entry and subtropical environment as well as complex drug induced diseases and atypical presentation of paraneoplastic diseases and atypical cutaneous tumors.
担 当
皮膚科学教室 教室
責任者：天谷 雅行 教授
担当者：大内 健嗣 先生（内線 62413）
責任者：天谷 雅行 教授
担当者：大内 健嗣 先生（内線 62413）
2024年12月6日（金） 16:00 開催
場 所
総合医科学研究棟 ラウンジ
演 題
Pioneering the Future of Cancer Immunotherapy: A New Era of Synthetic Immunology through Computational Modeling
Taisuke Kondo D.V.M., Ph.D
Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health
Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health
Chimeric Antigen Receptor (CAR) T-cell immunotherapy has revolutionized the treatment of hematological malignancies. However, its application to solid tumors has been hindered by poor specificity and potential toxicity to healthy tissues. To address these limitations, we developed an integrated approach combining a high-throughput robotic platform with mathematical modeling to systematically evaluate and optimize T-cell function. This novel approach enabled us to uncover previously unknown signaling crosstalk within CAR T-cells, leading to the development of an optimized CAR design. Our enhanced CAR T-cell platform demonstrates significantly improved anti-tumor activity while minimizing toxicity to healthy tissues. These findings highlight the power of computational modeling in simulating immune cell behaviors and provide a robust framework for designing more precise and effective cancer immunotherapies.
担 当
先端医科学研究所 がん免疫研究部門 教室
責任者：籠谷 勇紀 教授（内線 63652）
責任者：籠谷 勇紀 教授（内線 63652）
以上